RenoPlayer,
Hi,
I was in Tunica last July and stayed at the Horseshoe on the way out for a sister's road trip and stopped at Sam's Town on the way back home. For me, I enjoyed the room at the Horseshoe better because they had refrigerators in the rooms and Sam's Town did not, also the Horseshoe just seemed to be a bit more updated. It is also right next to the Gold Strike and the Sheraton so it was very easy to go in and out of those 3 without having to travel. Sam's Town does have the Hollywood and another casino across the street but it's a good long walk to get there without having to drive over.
Other than using a coupon from ACG for a buffet at the Fitz, we didn't get to any other casinos.
Enjoy the trip wherever you stay.
bb1mac